Skip to content

Investigating the effect of premedication with ibuprofen suspension in reduction of pain during vital pulp therapy of MIH-affected mandibular first permanent molar in 6-9 years old children

Investigating the effect of premedication with ibuprofen suspension in reduction of pain during vital pulp therapy of MIH-affected mandibular first permanent molar in 6-9 years old children

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250308064976N1
Enrollment
32
Registered
2025-04-22
Start date
2025-04-20
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dental decay. Dental caries

Interventions

Intervention 1: Intervention group:the ibuprofen suspension (100 mg/5 cc, Alhavi Pharmaceutical Co., Tehran, Iran) will have a strawberry flavor drug dosage will be calculated based on the patient’s w

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 9 Years

Inclusion criteria

Inclusion criteria: Children aged 6 to 9 years with MIH whose permanent lower molars have fully erupted There is a lower 6th tooth that requires vital pulp therapy and the treatment of each tooth is completed in one session. Children with teeth suitable for restoration, no sensitivity to percussion, and clinical symptoms, no radiographic signs, no signs of pulp necrosis, including no fistula and no abnormal bleeding from the canals during cavity preparation. Also, the child has not taken any medication in the past 24 hours before the visit.

Exclusion criteria

Exclusion criteria: Any systemic disease that contraindicates conservative pulp therapy, or radiographic findings such as internal resolution, increased PDL space, furcation or periapical radiolucency, and root canal calcification

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: during treatment. Method of measurement: sound eye motor.

Secondary

MeasureTime frame
Pain score. Timepoint: Before and during treatment. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhaneh Faghihian

Esfahan University of Medical Sciences

r.faghihian@dnt.mui.ac.ir+98 913 205 3106

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jul 4, 2026