Burn. Corrosions classified according to extent of body surface involved
Conditions
Interventions
Intervention 1: Intervention Group: In the intervention group, the treatment protocol will consist of a two-stage process specifically designed to treat keloids. First, the existing keloid tissue will
Sponsors
Vice President for Research and Technology, Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with keloid scars visiting Amir al-Muminin Hospital, Shiraz, Iran Consent of the patient or the patient's legal guardian to participate in the study Patients who have keloids in two areas of the body, and these two areas are distant from each other.
Exclusion criteria
Exclusion criteria: Pregnant and breastfeeding women Patients with connective tissue diseases such as lupus and scleroderma Patients with vasculitis Presence of a pacemaker at the radiotherapy site Patients with a history of hypersensitivity to radiotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Keloid scar recurrence rate. Timepoint: Patients are examined before the intervention, one day after the intervention, and every month for 6 months after the start of the study. Method of measurement: The POSAS (The Patient and Observer Scar Assessment Scale) is a comprehensive tool used to evaluate scar quality from both the patient's and the observer's perspectives. It consists of two parts: the Patient Scale, which assesses the patient's subjective experience of the scar, including pain, itching, and overall appearance, and the Observer Scale, which evaluates objective characteristics such as pigmentation, thickness, and pliability. Each scale provides a score, and the combined results offer a detailed assessment of the scar's impact and quality. POSAS is widely used in clinical and research settings for all types of scars, including those caused by burns, surgery, or trauma, making it a reliable and versatile instrument for scar evaluation.;Keloid scar recurrence time. Timepoint: Before the intervention, one day after the intervention, and then at regular intervals every month up to 6 months. Method of measurement: The POSAS (The Patient and Observer Scar Assessment Scale) is a comprehensive tool used to evaluate scar quality from both the patient's and the observer's perspectives. It consists of two parts: the Patient Scale, which assesses the patient's subjective experience of the scar, including pain, itching, and overall appearance, and the Observer Scale, which evaluates objective characteristics such as pigmentation, thickness, and pliability. Each scale provides a score, and the combined results offer a detailed assessment of the scar's impact and quality. POSAS is widely used in clinical and research settings for all types of scars, including those caused by burns, surgery, or trauma, making it a reliable and versatile instrument for scar evaluation.;Treatment response rate. Timepoint: Before the intervention, one day after the intervention, and then at | — |
Secondary
| Measure | Time frame |
|---|---|
| Radiotherapy complications in keloids treatment. Timepoint: Before the intervention, one day after the intervention, and then at regular intervals every month up to 6 months. Method of measurement: The POSAS (The Patient and Observer Scar Assessment Scale) is a comprehensive tool used to evaluate scar quality from both the patient's and the observer's perspectives. It consists of two parts: the Patient Scale, which assesses the patient's subjective experience of the scar, including pain, itching, and overall appearance, and the Observer Scale, which evaluates objective characteristics such as pigmentation, thickness, and pliability. Each scale provides a score, and the combined results offer a detailed assessment of the scar's impact and quality. POSAS is widely used in clinical and research settings for all types of scars, including those caused by burns, surgery, or trauma, making it a reliable and versatile instrument for scar evaluation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbdolkhalegh Keshavarzi
Shiraz University of Medical Sciences
Outcome results
None listed