Suicidal ideation. Suicidal ideations
Conditions
Interventions
rTMS protocol: The rTMS intervention will be 120% of motor threshold on the left prefrontal cortex, with a stimulation frequency of 10 Hz, each train will be 5 seconds long, with a 10 second interval
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age more than 18 years Age less than 70 years Fluency in Persian A minimum score of 12 on the Beck Suicidality Disorders Scale and a minimum score of 3 on the Hamilton Rating Scale The patient must be in an evaluation period (unipolar or bipolar, without psychosis) according to DSM-5.)
Exclusion criteria
Exclusion criteria: Age less than 18 years Age more than 70 years Diagnosis of other psychiatric disorders (borderline personality disorder, schizophrenia, bipolar type 1, dementia) History of epilepsy in oneself or a first-degree relative Drug dependenceSubstance abuse within 6 days before the start of the study Alcohol consumption with unstable vital signs and signs of alcohol withdrawal Neurological disorder or severe physical problems Those who cannot tolerate rTMS stimulation Taking medications that lower the seizure threshold Presence of a magnetic source or metal splinter in the head, and a cardiac pacemaker Pregnancy Individuals who do not meet the conditions for consent are also not included in the study If a seizure occurs during the intervention, the individual will be removed from the study and will continue their drug treatment at an adequate dose
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Studying the effect of high dose repetitive transcranial magnetic stimulation on the Beck Suicide Scale. Timepoint: The Beck Suicidality Scale will be measured for all study participants (in the sham and treatment groups) a total of 9 times. This scale will be filled out for inpatients at the beginning and end of each day of treatment, before discharge, one week after discharge, and four weeks after discharge. In outpatients, the Beck Suicidality Scale will be filled out at the beginning, end of each day of treatment, one week after the end of treatment, and four weeks after the end of treatment. Method of measurement: Beck suicide scale questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Studying the effect of high-dose repetitive transcranial magnetic stimulation on the Hamilton Depression Rating Scale. Timepoint: The Hamilton Depression Rating Scale will be completed a total of 5 times for all study participants (in both sham and treatment groups) to assess the effectiveness of the rTMS intervention. In inpatients, it will be completed at baseline, at the end of treatment, before discharge, one week after discharge, and one month after discharge. In outpatients, it will be completed at baseline, at the end of treatment, one week after the end of treatment, and one month after the end of treatment. Method of measurement: Hamilton Depression Rating Scale.;Studying the effect of high-dose repetitive transcranial magnetic stimulation on the Columbia Suicidality Severity Rating Scale. Timepoint: The Columbia Suicidality Severity Scale (CSSS) will be administered to all study participants (both sham and treatment) a total of 5 times per treatment to assess the effectiveness of the rTMS intervention. In outpatient settings, it will be completed by patients at baseline, end of treatment, one week after the end of treatment, and one month after the end of treatment. Method of measurement: Columbia Suicidality Severity Rating Scale.;Determining the side effects of high-dose repetitive transcranial magnetic stimulation on the left prefrontal cortex. Timepoint: This checklist will be completed a total of 5 times for all study participants (in both the sham and treatment groups). In inpatients, it will be measured at the end of each treatment day, at discharge, one week after discharge, and four weeks after discharge. This investigator-constructed checklist will be completed in outpatients, at the end of each treatment day, one week after the end of treatment, and four weeks after the end of treatment. Method of measurement: Checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mohaddeseh Ebrahimpour rodposhti
Tehran University of Medical Sciences
Outcome results
None listed