solar lentigines of the dorsal hands. Other melanin hyperpigmentation
Conditions
Interventions
Intervention 1: Intervention group: In the intervention side, carboxytherapy will be performed every two weeks. Treatment in the carboxytherapy area will continue every two weeks for up to five sessio
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to No maximum
Inclusion criteria
Inclusion criteria: Presence of relatively symmetrical solar lentigines on the back of the hands
Exclusion criteria
Exclusion criteria: The presence of active skin infections in the area where carboxytherapy is performed. Suffering from any systemic disease such as diabetes, kidney disease, heart disease, respiratory disease, liver disease, severe anemia, etc. Suffering from any vascular diseases or events such as embolism and vascular thrombosis. Having connective tissue diseases or genodermatoses. Tendency to form keloids. Medication therapy (including dietary supplements) from 6 weeks before the start of the study. History of any treatment for solar lentigo within 6 weeks prior to the start of the study. Smoking, alcohol consumption, and drug abuse. Pregnancy Breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of lentigo macules. Timepoint: Clinical examination and high-resolution digital photography will be used at time 0, before each carboxytherapy session (weeks 2 to 8), and two weeks after the last session to evaluate the outcomes. Patients will be monitored for three months from enrollment. Method of measurement: through digital image analysis across different sessions and recorded by the student. | — |
Secondary
| Measure | Time frame |
|---|---|
| The overall improvement score of solar lentigines is assessed based on a standardized scoring system. Timepoint: The overall improvement score of lentigo is measured from the second session onward and two weeks after the last treatment session?. Method of measurement: The overall improvement score of lentigo is measured using a numerical grading scale (0 to 6), which determines the extent of improvement or worsening of lesions. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehdi Hosseini
Arak University of Medical Sciences
Outcome results
None listed