????? ???????? ? ??????? ????. Atrophic disorder of skin, unspecified
Conditions
Interventions
Intervention 1: Intervention Protocol: In this study, botulinum toxin type A (Masport®, Masoon Darou Pharmaceutical Co.) was used for treatment. Each 500-unit vial was initially diluted with 3.4 mL of
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: Presenting with moderate to severe erythematous atrophic scarring on both sides of the face.
Exclusion criteria
Exclusion criteria: Use of topical medication on the scar site
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acne scar erythema. Timepoint: Evaluation of acne scar erythema will be performed at four time points: before treatment initiation (baseline), then at 1 month, 2 months, and 3 months after Mesobotox treatment. Method of measurement: In this study, standardized clinical photographs of lesions are obtained at four time points: baseline (treatment initiation), 1-month, 2-month, and 3-month follow-ups. All photographic documentation is performed under consistent lighting conditions. These images are subsequently evaluated by two board-certified dermatologists specializing in acne scar management, who grade erythema severity using a validated 4-point scale (0: no erythema, 1: mild erythema, 2: moderate erythema, 3: severe/dark red erythema).Concurrently, Visioface® imaging system documentation is performed at all four evaluation timepoints (baseline, months 1, 2, and 3) to provide objective erythema measurements through standardized facial imaging. Additionally, patients complete a Visual Analog Scale (VAS) for self-assessment of erythema severity at both baseline and treatment completion, where 0 represents minimal erythema and 10 indicates maximal erythema severity. This multimodal assessment approach - incorporating expert clinician ratings, objective Visioface® measurements, and patient-reported outcomes - enables comprehensive longitudinal evaluation of acne scar erythema improvement throughout the treatment course. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contact????? ??????? ??????
Tehran University of Medical Sciences
Outcome results
None listed