The effect of booster vaccine HBV in pediatrics with autoimmune hepatitis

Assessment of hepatitis B antibody level and evaluation of booster vaccine response in pediatrics with autoimmune hepatitis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250302064902N1

Enrollment

145

Registered

2025-03-06

Start date

2025-04-05

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autoimmune hepatitis. Autoimmune hepatitis

Interventions

Intervention group: Children aged 1 to 18 years with autoimmune hepatitis with a serum HBS Ab level less than 10 mIU/ml. A booster dose of hepatitis B vaccine of one milliliter (20 micrograms) is admi

Eligibility

Sex/Gender

All

Age

1 Years to 18 Years

Inclusion criteria

Inclusion criteria: Having autoimmune hepatitis Being between 1 and 18 years old

Exclusion criteria

Exclusion criteria: Being positive HBS Ag

Design outcomes

Primary

Measure	Time frame
Serum level HBS Ab. Timepoint: At the beginning of the study and 30 to 60 days after receiving the vaccine. Method of measurement: Antibody level are measured by ELISA method using a Pishtaz kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahboobeh Moazeni

Shahid Beheshti University of Medical Sciences

m.moazeni.mm@gmail.com+98 21 2222 7021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026