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Effect of Empagliflozin on Atrial Fibrillation Rhythm

Investigation of the Effect of Empagliflozin on Atrial Fibrillation Rhythm in Patients After Coronary Artery Bypass Surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250302064896N6
Enrollment
100
Registered
2025-12-02
Start date
2025-11-22
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation (AF). atrial fibrillation (AF)

Interventions

Intervention 1: Intervention group: Patients in this group will receive a daily 10 mg tablet of empagliflozin (brand name: Gloripa), manufactured by Abidi Pharmaceutical Company. Administration begins

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 to 70 years who are candidates for coronary artery bypass graft surgery (coronary artery bypass grafting; CABG).

Exclusion criteria

Exclusion criteria: Patients with left ventricular dysfunction. Patients with left atrial enlargement. Patients with chronic kidney disease and a glomerular filtration rate (GFR) below 30 mL/min Patients with a history of atrial fibrillation. Patients with chronic obstructive pulmonary disease (COPD) Patients with a history of urinary tract infection (UTI). Patients with liver failure. Patients with mitral valve disease of more than moderate severity

Design outcomes

Primary

MeasureTime frame
The primary outcome variable in this study is the occurrence of atrial fibrillation (AF) after coronary artery bypass graft surgery (CABG). This variable is identified and documented by a cardiologist based on electrocardiographic (ECG) evidence and recorded episodes of atrial fibrillation within 48 to 72 hours postoperatively. Timepoint: Atrial fibrillation will be measured and recorded at the following time points:Before coronary artery bypass graft surgery (as baseline)48 hours after surgery72 hours after surgery. Method of measurement: Atrial fibrillation will be measured using a standard twelve-lead electrocardiogram device at the specified time points. Final diagnosis will be made by a cardiologist based on electrocardiogram interpretation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmadreza Assareh

Ahvaz University of Medical Sciences

dr_assarreh@ajums.ac.ir+98 61 3339 4810

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026