Contrast-induced nephropathy. Contrast-induced nephropathy
Conditions
Interventions
Intervention 1: Intervention group: Saline (0.45%) was given intravenously at a rate of 1 ml per kg of body weight per hour and grapefruit seed extract was given orally at a dose of 500 mg 6 hours bef
Ultravist-300, brand name Visipaqe) was 75 ml for all patients. Intervention 2: Control group: Saline (0.45%) was given intravenously at a rate of 1 ml per kg body weight per hour and placebo was give
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: age over 18 years People with a glomerular filtration rate between 30 and 60 Absence of acute renal failure at baseline
Exclusion criteria
Exclusion criteria: The patient's unwillingness to continue cooperating Patients taking nephrotoxic drugs including vancomycin, aminoglycosides, colistin Patients with multiple myeloma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Protective effect of grapefruit seed extract on the prevention of contrast-induced nephrotoxicity. Timepoint: Serum creatinine measurement before the start of the intervention and 48 hours after the intervention. Method of measurement: Serum creatinine measurement. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamia Shabib
Arak University of Medical Sciences
Outcome results
None listed