Ectopic Pregnancy. Ectopic pregnancy, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Without the need for general anesthesia and, if necessary, under local analgesia, and after confirming blood flow in the gestational sac area during a transvaginal
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Consent to treatment Women aged between 18 to 45 Gestational age between 5 to 10 weeks Hemodynamically stable One of the criteria below that candidates the patient for a laparoscopic surgery in a conventional center: Patient preference, Allergy to MTX, Concurrent intrauterine pregnancy, Lactating, Active Lung disease, Renal disease, Chronic hepatic disorder, Blood dyscrasia, Immune deficiency, Gastric peptic ulcer, Serum ß-hCG level above 3510 mIU/mL, Mass size greater than 3.5 cm, Detectable fetal heartbeat.
Exclusion criteria
Exclusion criteria: Patient's refusal to participate Lost to follow-up Gestational age below 5 or over 10 weeks Suspected fallopian tube rupture, i.e., the presence of hemodynamic instability, heavy bleeding, altered level of consciousness, severe abdominal pain and tenderness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maternal serum ß-hCG level. Timepoint: Two hours after the injection, the patients' serum ß-hCG levels are checked. If a 20% decrease compared to the baseline level is not observed, a second injection is administered following the same protocol. Subsequently, the patients' serum ß-hCG levels are checked on days 1, 4, and 7 after the injection and then weekly until they become negative. Method of measurement: Enzyme immunoassay. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzadeh Tarafdari Manshadi
Tehran University of Medical Sciences
Outcome results
None listed