Effect of Tranexamic acid on healing of bone fracture

Investigating the effect of local tranexamic acid on the repair of long bone fractures of the lower limb

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250226064858N1

Enrollment

100

Registered

2025-03-12

Start date

2025-03-13

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tibia and femur fractures.

Interventions

Intervention group: recipient of tranexamic acid.

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Desire to participate in study Age 18 to 50 years old fracture of tibia or Femur bone

Exclusion criteria

Exclusion criteria: Using other drugs for fracture healing Re-farcture and Re surguery during study Not reffering for X-Ray examination

Design outcomes

Primary

Measure	Time frame
In order to check the radiographic findings of the patients, the scoring system of Lane and Sandh will be used, which will be done by the radiologist. This system is based on a scale of 0 to 12 points using three dimensions: bone formation in the fracture gap, the presence of a fracture line, and evidence of reconstruction, which will be calculated by adding scores from all three parameters to calculate the total fracture repair score. It should be noted that the higher the Lane and Sandh scores of the patients, the better the fracture repair status. Timepoint: Investigation of bone union in the second week and months 2-4-7. Method of measurement: Lane and Sandh scoring system.	—

Measure

Time frame

In order to check the radiographic findings of the patients, the scoring system of Lane and Sandh will be used, which will be done by the radiologist. This system is based on a scale of 0 to 12 points using three dimensions: bone formation in the fracture gap, the presence of a fracture line, and evidence of reconstruction, which will be calculated by adding scores from all three parameters to calculate the total fracture repair score. It should be noted that the higher the Lane and Sandh scores of the patients, the better the fracture repair status. Timepoint: Investigation of bone union in the second week and months 2-4-7. Method of measurement: Lane and Sandh scoring system.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Sirgani

Arak University of Medical Sciences

majidsirgani59@gmail.com+98 86 3366 6805

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026