Therapeutic Abortion. (Induced) termination of pregnancy with unspecified complications
Conditions
Interventions
Intervention 1: Intervention Group 1: Misoprostol Combined with Evening Primrose OilTreatment Method:In this group, a combination of misoprostol and evening primrose oil is used.Misoprostol:Dose: 200
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 40 years Candidate for therapeutic abortion (based on the specialist’s evaluation) Gestational age less than 20 weeks No contraindications for Misoprostol or Evening Primrose (e.g., patients with respiratory diseases or asthma are excluded) Providing informed consent to participate in the study Availability for follow-up and monitoring
Exclusion criteria
Exclusion criteria: Participants who do not provide consent to participate in the study. Participants who are lost to follow-up during the study Patients with contraindications to receiving evening primrose oil or misoprostol, such as those with pulmonary diseases or asthma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of pregnancy termination Definition: The percentage of patients who achieve complete pregnancy termination with the assigned treatment (Misoprostol alone or Misoprostol with Evening Primrose), without the need for additional interventions (e.g., curettage). Timepoint: 24 to 48 hours after the start of treatment. Method of measurement: Percentage (%). | — |
Secondary
| Measure | Time frame |
|---|---|
| Time required for pregnancy termination Definition: The duration from the start of treatment to the complete termination of pregnancy (complete expulsion of pregnancy products). Timepoint: From the start of treatment until pregnancy termination. Method of measurement: Hours.;Need for additional intervention Definition: The number of patients requiring additional interventions (e.g., curettage or surgery) after treatment. Timepoint: Within 7 days after the start of treatment. Method of measurement: Number (n).;Patient satisfaction Definition: The level of patient satisfaction with the treatment method, assessed using a standardized questionnaire. Timepoint: After completing the treatment. Method of measurement: Score (Scale 1-10).;Rate of side effects Definition: The percentage of patients experiencing treatment-related side effects (e.g., nausea, vomiting, diarrhea, or severe bleeding). Timepoint: Within 72 hours after the start of treatment. Method of measurement: Percentage (%). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzar Danesh Shahraki
Esfahan University of Medical Sciences
Outcome results
None listed