Investigating the effect of nitrous oxide gas on increasing laryngeal mask cuff pressure during general anesthesia.

Investigating the effect of nitrous oxide gas on increasing the pressure of the laryngeal mask cuff during general anesthesia with inhaled anesthetics and the occurrence of sore throat.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250224064836N1

Enrollment

Registered

2025-03-07

Start date

2025-04-04

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

LMA cuff pressure increase.

Interventions

Intervention 1: Intervention group: The study group receives N20 gas at a dose of 70%. Intervention 2: Control group: Patients receive 100% oxygen.

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: All patients were between 15-60 years of age, ASA class 1 or 2, weighing between 30 and 100 kg, and had informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: Lack of informed consent Full stomach or emergency patient Surgery in the prone or lateral position Head, neck, and airway trauma Low airway resistance and lung compliance

Design outcomes

Primary

Measure	Time frame
Sore throat. Timepoint: After laryngeal mask airway removal and recovery. Method of measurement: According to clinical symptoms.;Cough. Timepoint: After laryngeal mask airway removal and recovery. Method of measurement: According to clinical symptoms.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Mehdi Hosseini

Gorgan University of Medical Sciences

drmahdi206@gmail.com+98 17 3115 3455

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026