Methamphetamine dependence. Other stimulant related disorders
Conditions
Interventions
Intervention 1: Intervention group: In this group of patients (n=40) will be requested to take two crocin tablets daily for 8 weeks (each tablet contain 15 mg crocin). The crocin tablets will be produ
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 55 Years
Inclusion criteria
Inclusion criteria: Aged 25 to 55 Patients with addiction (Evaluated by the drug abuse section of the Structured Clinical Interview for DSM-IV) Complete informed consent Patients using methamphetamine and amphetamine (test positive for methamphetamine) Seeking for treatment
Exclusion criteria
Exclusion criteria: Unwillingness to cooperate Patients with psychiatric, psychotic, and bipolar disorders Suicide attempts Consumption of crocin, anti-inflammatory, and antioxidant supplements during the last 3 months Users of warfarin Having high blood pressure and thyroid disease Positive urine test for cannabis People who are allergic to the study supplement and report side effects from taking the medication during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Withdrawal. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Amphetamine Withdrawal Questionnaire (AWQ).;Craving. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Desire for Drug Questionnaire (DDQ craving). | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Cognitive abilities questionnaire (CAQ).;Mental health. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Depression Anxiety Stress Scales (DASS) questionnaire.;Sleep Quality. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Pittsburgh Sleep Quality Index (PSQI) questionnaire.;Sexual function. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: International Index of Erectile Function (IIEF) questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Ghaderi
Kashan University of Medical Sciences
Outcome results
None listed