Premenstrual dysphoric disorder. Other specified mood [affective] disorders
Conditions
Interventions
Intervention 1: Patients in this group receive fluoxetine boosted with scopolamine. Dosage: 0.5 mg scopolamine + fluoxetine, taken as 2 tablets per day. Objective: To investigate the effect of this dr
Sponsors
Zahedan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Women aged 18 to 40 with premenstrual dysphoric disorder Informed consent to participate in the study No history of tobacco, caffeine, or alcohol use in the past month. No history of taking medications such as OCPs, antidepressants, analgesics, antispasmodics, and GnRH analogs in the past month. No history of uterine and ovarian diseases such as myomas, polycystic ovary syndrome, endometriosis, infections, polyps, and cancer. No history of uterine and ovarian diseases such as myomas, polycystic ovary syndrome, endometriosis, infections, polyps, and cancer. No history of surgical interventions such as hysterectomy and various methods of endometrial ablation or resection No history of using levonorgestrel-releasing intrauterine devices in the past month
Exclusion criteria
Exclusion criteria: Unwillingness to continue cooperation in any stage of the research Observation of serious side effects of hyoscine during research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of premenstrual symptoms. Timepoint: Daily symptom recording form. Method of measurement: In the first interview, if the conditions for entry into the study are met, two questionnaires are filled out by the patient and the doctor, and then, depending on the menstrual cycle, they are checked again immediately after the end of the second cycle, between 42-70 days later.;Premenstrual dysphoric disorder score. Timepoint: Daily symptom recording form. Method of measurement: Standard PMDD screening questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMona Mahdavian
Zahedan University of Medical Sciences
Outcome results
None listed