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Investigation of the effectiveness of royal gel on the sensation of dry mouth in patients who referred to the department of oral diseases of Zahedan Faculty of Dentistry in 2025

Investigation of the effectiveness of royal gel on the sensation of dry mouth in patients who referred to the department of oral diseases of Zahedan Faculty of Dentistry in 2025

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250218064770N1
Enrollment
16
Registered
2025-08-03
Start date
2025-08-19
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry mouth.

Interventions

Intervention group: In this interventional study, people with dry mouth who are referred to the oral diseases department will be included in the study. The inclusion criteria include the following: no

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: No use of any tobacco products No systemic diseases affecting the salivary glands such as (diabetes, Sjogren's, no use of medications that cause dry mouth, no candidiasis and asthma) Good oral hygiene and pocket depth less than 3 mm No use of supplements in the past 3 months No food allergies

Exclusion criteria

Exclusion criteria: Non-cooperation of individuals in regular medication use Consumption of any tobacco products Presence of systemic diseases affecting the salivary glands such as (diabetes, Sjogren's, use of medications that cause dry mouth, candidiasis and asthma) Non-compliance with proper oral hygiene and pocket depth greater than 3 mm Consumption of supplements in the past 3 months Presence of food allergies

Design outcomes

Primary

MeasureTime frame
Non-stimulated saliva volume. Timepoint: In the study (Effectiveness of Royal Jelly Supplementation on Dry Mouth), the time points for measuring non-stimulated gloss volume were at the beginning of the study (before the intervention) and 30 days after the start of royal jelly supplementation. Method of measurement: In the study (Effectiveness of Royal Jelly on Dry Mouth), the method of measuring the variable of non-stimulated saliva volume was to collect saliva inside the mouth by spitting into a sampling container, which was measured on a cc scale.;Dry mouth. Timepoint: In the study (Effectiveness of Royal Jelly Supplement on Dry Mouth), the time points for measuring dry mouth were at the beginning of the study and 30 days after starting to take the royal jelly supplement. Method of measurement: In the study (Effectiveness of Royal Jelly on Dry Mouth), the method of measuring the dry mouth variable is based on a standard questionnaire to assess the presence of dry mouth. If the patient answers positively to at least 3 questionnaires, he is considered to have dry mouth.;Measurement stage. Timepoint: In the study (Effectiveness of Royal Jelly Supplement on Dry Mouth), the time periods for the measurement stage variable are at the beginning of the study and 30 days after taking the royal jelly supplement. Method of measurement: In the study (Effectiveness of Royal Jelly Supplement on Dry Mouth), the variable was measured based on the length of time since taking the medication.;Gender. Timepoint: In the study (Effectiveness of Royal Jelly Supplement on Dry Mouth), the time points for measuring the gender variable are only at the beginning of the study. Method of measurement: In the study (Effectiveness of Royal Jelly on Dry Mouth), the method of measuring the gender variable is based on asking the patient.;Age. Timepoint: In the study (Effectiveness of Royal Jelly Supplementation on Dry Mouth), the time points for measuring the age variable are only at the beginning of

Secondary

MeasureTime frame
Unstimulated saliva volume. Timepoint: In the study (Investigating the effectiveness of royal jelly supplementation on dry mouth), the time points for measuring non-stimulated gloss volume can be at the beginning of the study (before the start of the intervention) and 30 days after starting to take the royal jelly supplement. Method of measurement: In the study (Investigating the effectiveness of royal jelly on the feeling of dry mouth), the method of measuring the variable of non-stimulated saliva volume was to collect saliva inside the mouth by spitting into a sampling container, which was measured on a cc scale.;Dry mouth. Timepoint: In the study (Investigating the effectiveness of royal jelly supplementation on dry mouth), the time points for measuring dry mouth were at the beginning of the study and 30 days after starting to take the royal jelly supplement. Method of measurement: In the study (Investigating the effectiveness of royal jelly on dry mouth), the method of measuring the dry mouth variable is based on a standard questionnaire to assess the presence of dry mouth. If the patient answers positively to at least 3 questionnaires, he is considered a patient with dry mouth.;Measurement step. Timepoint: In the study (Investigating the effectiveness of royal jelly supplementation on dry mouth), the time periods for the measurement stage variable are at the beginning of the study and 30 days after taking the royal jelly supplement. Method of measurement: In the study (Investigating the effectiveness of royal jelly supplementation on dry mouth), the variable was measured based on the length of time since taking the medication.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoheila Hanafi

Zahedan University of Medical Sciences

Hanafisoheila78@gmail.com+98 54 3348 4580

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026