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Comparing the Effects of Six Weeks of Closed Kinetic Chain training, Neurofeedback training and their combination on Pain, Movement Function, Balance and Quality of Life in Women Affected by Knee Osteoarthritis.

Comparing the Effects of Six Weeks of Closed Kinetic Chain training, Neurofeedback Itraining, and their combination on Pain, Movement Function, Balance and Quality of Life in Women Affected by Knee Osteoarthritis.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250218064767N1
Enrollment
60
Registered
2025-04-29
Start date
2025-05-22
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis.. Osteoarthritis, unspecified site

Interventions

Intervention 1: Intervention group:First Intervention CKC Exercises: Subjects will receive the CKC exercise program, which includes exercises such as squats, lunges, bridges, and stair climbing, for s

Sponsors

The University of Razi
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: Definitive diagnosis of knee osteoarthritis by a specialist physician in accordance with the diagnostic criteria of the American College of Rheumatology for knee osteoarthritis. Age 50 to 70 years. Ability to perform CKC exercises.

Exclusion criteria

Exclusion criteria: No neurological (Parkinson's and MS), cardiovascular or musculoskeletal (stroke) diseases that prevent participation in the study. No use of anti-inflammatory drugs or narcotic analgesics in the two weeks prior to the start of the study. No history of brain tumor, brain surgery or intracranial metal implantation in the past. No history of knee replacement surgery. No cognitive disorders. No use of psychotropic or antihypertensive drugs (antidepressants, antipsychotics, antiparkinsonians, tranquilizers and strong hypnotics). No history of surgery in the lower extremities.

Design outcomes

Primary

MeasureTime frame
Pain intensity: A visual analogue scale (VAS) will be used to measure pain intensity. Timepoint: At the beginning and end of the study. Method of measurement: This scale is a 10 cm horizontal line with "no pain" written at the beginning and "worst imaginable pain" written at the end. Participants indicate their level of pain by marking this line.;Performance: One of the indicators for evaluating functional capacity in patients with knee osteoarthritis is the use of the WOMAC questionnaire. Timepoint: At the beginning and end of the study. Method of measurement: The Womack scale consists of five-item questionnaires that grade the severity of symptoms from none to 4 (very severe), and the patient selects one of them based on the severity of their symptoms. The Womack scale has three subscales: pain with a score of (20), stiffness with a score of joint stiffness (0-8), and physical function with a score of (0-68). A higher score indicates more severe symptoms.;Assessment of knee instability using the Fulkerson questionnaire. Timepoint: At the beginning and end of the study. Method of measurement: This questionnaire includes a question about the degree of knee flexion, buckling, or displacement and its impact on daily activities. Knee instability Knee instability will be self-reported based on the Felson questionnaire. This scale is graded in response to the question "Does the degree of knee flexion, buckling, or displacement affect your daily activities?" as follows: 5 "I have no symptoms," 4 "I have symptoms but they do not affect my daily activities," 3 "My symptoms slightly affect my daily activities," 2 "My symptoms moderately affect my daily activities," 1 "My symptoms strongly affect my daily activities," and 0 "My symptoms prevent me from doing all my daily activities.;Balance: Will be used to assess balance (postural control) in a static position. Timepoint: At the beginning and end of the study. Method of measurement: Static balance will be measured in 2 posit

Secondary

MeasureTime frame
Fearful movement. Timepoint: At the beginning and end of the study. Method of measurement: To complete the assessment of agoraphobia, we will use the Tampa questionnaire. Validity and reliability of the Persian version of the TSK 17 questionnaire is a 17-item scale, each item is answered on a four-point Likert scale. It is scored in a four-point range (1 means completely disagree to 4 means completely agree). The final score is 17-68. Scores higher than 37 indicate a high degree of agoraphobia. Its 1, 2 and 4-factor structural models have been implemented. Among them, the two-factor model is more preferable and is more commonly used due to its adaptation to the patient's conditions and different situations. The two-factor model includes two subscales, concentration and physical belief of PSF damage, which actually indicates the belief that pain is a sign of some kind of injury, damage or problem in the body system, and the second subscale is activity avoidance, which indicates the belief that any activity that causes increased pain should be avoided.;Quality of life. Timepoint: At the beginning and end of the study. Method of measurement: The Knee and Hip Osteoarthritis Quality of Life Inventory (OAKHQoL) developed by French researchers is multidimensional and covers all the dimensions that have been highlighted for patients with lower extremity osteoarthritis. They have proven that this tool is a successful tool for measuring quality of life in knee and hip osteoarthritis patients. The questionnaire consists of 43 questions, in which 40 items are divided into five domains: 16 physical activity, 13 mental health, 4 pain, 4 social support, 3 social activities and 3 independent items on professional life, sexual activity and relationships. Each question is given a response scale of 0 to 10 points, where 0 determines the worst situation and 10 the best situation. The score of each dimension is standardized on a scale of 0 (worst level of quality of life) to 100 (best l

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArezoo Afrazi

The University of Razi

afrazi.arezoo@gmail.com+98 83 3723 5588

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026