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Comparing the effect of morphine with a combination of Ketorolac and Plazil on pain in renal colic patients

Comparison of the effect of morphine with the combination of ketorolac and Metoclopramide on the pain of renal colic Patients

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250217064752N1
Enrollment
50
Registered
2025-03-12
Start date
2025-04-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal colic. Unspecified renal colic

Interventions

Intervention 1: First intervention group: Ketorolac and metoclopramide. In this intervention, a 30 mg Ketorolac ampoule and a 10 mg metoclopramide ampoule are drawn together in a 5 cc syringe and mixe

Sponsors

Gonabad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to No maximum

Inclusion criteria

Inclusion criteria: The presence of clinical symptoms of renal colic in the patient and at least one of the following three conditions: hematuria on a complete urinalysis, stones seen on the patient's radiograph, or renal ultrasound. - Age over 16 years old - Absence of concomitant disease that causes similar pain - Willingness to collaborate in research

Exclusion criteria

Exclusion criteria: -Having inflammatory bowel disease or any disease that causes similar pain - Drug and alcohol addiction, pregnancy and breastfeeding - Taking any painkillers in the past 24 hours - History of allergy to ketorolac, morphine and metoclopramide - Proven mental and anxiety disorders - Willingness to continue collaborating in research -Sensitivity during injection

Design outcomes

Primary

MeasureTime frame
Pain - In this study, it refers to the score that the subjects will obtain from the visual analog scale. In this way, the level of pain on this scale will range from 0 (no pain) to 10 (maximum possible pain), and the patient will mark the level of pain at different intervals on this line, whose vanes are only visible at the beginning. Timepoint: Measurements are taken at the time of entry into the study, 20, 40, and 60 minutes after entering the emergency room. Method of measurement: Visual analog scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlaedin Abedini

Gonabad University of Medical Sciences

freshtehabedini1376@gmail.com+98 51 9993 2188

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026