Advanced cancer disease. Malignant neoplasms
Conditions
Sponsors
Khoram-Abad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: Advanced cancer diagnosis by an oncologist (based on the TMN score and type of cancer) Anorexia having a minimum score of 3 in the symptoms section (provided that the score of 3 pertains to anorexia or lack of appetite) Minimum score of 1 in the dietary intake section Minimum score of 0 in the recent current weight section Minimum score of 0 in the activity section (with a minimum total score of 4) in the PG-SGA questionnaire Patients aged 45-70 years with weight loss due to advanced cancer (weight loss of at least 2.5 kg over 6-8 weeks or weight loss of at least 5% over the last 6-12 months) Not using other appetite-stimulating and weight-gaining supplements during the study No history of allergy to L-Arginine, L-Carnitine, Omega-3, and Megestrol Acetate Willingness to participate in the study.
Exclusion criteria
Exclusion criteria: Patients' refusal during the study. Occurrence of side effects Development of acute liver and kidney diseases Development of coagulation disorders Non-use of L-Arginine, L-Carnitine, Omega-3, and Megestrol Acetate during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in the PG-SGA questionnaire score. Timepoint: At the beginning of the study (before the intervention started), 21 days and 31 days after the intervention began. Method of measurement: PG-SGA questionnaire.;Weight gain. Timepoint: At the beginning of the study (before the intervention started), 21 days and 31 days after the intervention began. Method of measurement: scale (for measuring weight changes). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Kharazmkia
Khoram-Abad University of Medical Sciences
Outcome results
None listed