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Dynamis Laser Combined with Hydroquinone in the Treatment of Axillary Hyperpigmentation

A Comparison of the Efficacy of 2% Hydroquinone Alone Versus 2% Hydroquinone Combined with Dynamis Laser in the Treatment of Axillary Hyperpigmentation in Patients Referred to Razi Dermatology Hospital

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250205064654N1
Enrollment
22
Registered
2025-07-21
Start date
2025-09-23
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Axillary Hyperpigmentation. Other melanin hyperpigmentation

Interventions

Intervention 1: Intervention group: Dynamis LASER + Hydroquinone 2% once in Razi LASER clinic. Intervention 2: Control group: Hydroquinone 2% made in compounding pharmacy department of raze skin hospi

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: The skin of the axilla is at least two shades darker than the surrounding normal axillary skin

Exclusion criteria

Exclusion criteria: Participants with systemic diseases, skin conditions affecting the axilla, acanthosis nigricans, or dermatologic disorders associated with abnormal hyperpigmentation (such as Riehl's melanosis or lichen planus pigmentosus) Participants receiving heavy metals (e.g., silver), chemotherapy, or antiretroviral medications that may cause increased pigmentation Pregnant or breastfeeding participants Participants undergoing ongoing treatment with topical lightening agents (such as vitamin C, hydroquinone, or retinoids) within two weeks prior to the study Participants who had received laser therapy or other dermatologic treatments in the axillary area within eight weeks prior to the study. Participants who experienced shoulder pain or stiffness

Design outcomes

Primary

MeasureTime frame
Axillary Hyperpigmentation improvement. Timepoint: aFTER TREATMENT AND 3 MONTH LATER. Method of measurement: Investigator evaluation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Fahimi

Tehran University of Medical Sciences

afshin.fahimi786@gmail.com+98 21 5288 8282

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026