The effect of Intrauterine injection of human chorionic gonadotropin before embryo transfer

The effect of Intrauterine injection of human chorionic gonadotropin before embryo transfer in paitent with 1 ET failure on pregnancy outcome

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250201064590N1

Enrollment

250

Registered

2025-02-08

Start date

2025-02-19

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

reccurent ivf failure.

Interventions

Intervention 1: Intervention group: HCG infusion intervention of 500 units will be performed. Intervention 2: Control group: Only an infusion of media will be performed 5-12 minutes before the embryo

Eligibility

Sex/Gender

Female

Age

No minimum to 41 Years

Inclusion criteria

Inclusion criteria: A history of failure in embryo transfer - Age =41-TSH and normal prolactin

Exclusion criteria

Exclusion criteria: Endometrial thickness less than 7 mm - Intrauterine adhesion - Uncontrolled chronic disease -Endometrial polyps or presence of submucosal myoma - Hydrosalpinx - Endometriosis grade 3 and above - Improper quality of the embryo

Design outcomes

Primary

Measure	Time frame
Determination and Comparison of Pregnancy Chemical Levels in Intervention and Control Groups. Timepoint: 14 day. Method of measurement: beta hcg titer.	—

Secondary

Measure	Time frame
Determination and Comparison of Pregnancy Ongoing in Intervention and Control Groups. Timepoint: 30 days. Method of measurement: trans vaginal sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactazadeh tarafdari

Tehran University of Medical Sciences

tarafdari@tums.ac.ir+98 21 6119

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026