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keratolytics for dermatophytosis

The Efficacy oral Terbinafine alone and combined with 20% topical urea in the treatment of Pediatric Dermatophytosis and Prevention of Chronicity and Recurrence. A double-blind Randomized control trail.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250131064579N1
Enrollment
140
Registered
2025-03-09
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dermatophytosis.

Interventions

Sponsors

Lady reading hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 14 Years

Inclusion criteria

Inclusion criteria: All patients with dermatophytes infection diagnosed on clinical grounds, between age2-14 and willing to participate in the study.

Exclusion criteria

Exclusion criteria: Patients with history of any topical or systemic antifungals used for the current infection, patients with diabetes mellitus or any other immunosuppression or having history of sensitivity to terbinafine or topical urea. Similarly, patients with past or current hepatitis or other liver diseases were considered ineligible for the trial. Finally patients with T.capitis and onychomycosis were not considered due to prolonged treatment regimes

Design outcomes

Primary

MeasureTime frame
Clinical improvement in skin lesions. Timepoint: Followup at weekly intervals and finally at 4thweek. Method of measurement: By assessing the parameters like complete remission(disappearance of all lesions),chronic and recurrent cases in both groups.

Secondary

MeasureTime frame
Chronicity and recurrence of dermatophytosis. Timepoint: 4 weekly and then finally at 6 months. Method of measurement: clinical assessment of recurrent and chronic cases in both groups.

Countries

Pakistan

Contacts

Public Contactaiza ur rahman

lady reading hospital

mr.aizazurrahman@gmail.com+92 302 8124881

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026