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evaluating the efficacy of platelet rich plasma injection accompanied with biofeedback therapy on fecal incontinence compared to biofeedback therapy alone

Evaluating the effectiveness of treatment of pelvic floor with simultaneous treatment with platelet-rich plasma and biofeedback in comparison to biofeedback as mono therapy rehabilitation of patients with fecal incontinence

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250127064537N1
Enrollment
40
Registered
2025-04-03
Start date
2025-04-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fecal incontinence. Fecal incontinence

Interventions

Intervention 1: Intervention group: The first group consists of 30 patients undergoing two sessions per week of pelvic floor muscle rehabilitation therapy. Each session lasts 30 minutes and follows a

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: all female patients with fecal incontinence Patients that fecal incontinence has affected their quality of their lives Patients who request non_surgical treatment for their fecal incontinence

Exclusion criteria

Exclusion criteria: Male patients Patients with gross rectal prolapse Patients with cervical or colorectal malignancy or dysplasia or history of pelvic radiation Patients with abnormal urine bleedings Pregnant patients Diabetic patients Patients with neurological disorders like SCI Patients with platelets disorders or other coagulation problems Patients with psychiatric problems Patients with active anorectal disorders

Design outcomes

Primary

MeasureTime frame
Improvement of sexual function and quality of life. Timepoint: 3 and 6 months after biofeedback therapy and platelet rich plasma injection. Method of measurement: Female sexual function index questionnaire and WHO quality of life questionnaire (WHo-QOL-BREF).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahsa Ghasemzadeh

Shiraz University of Medical Sciences

mahsaghasemzade27@gmail.com+98 930 587 8850

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026