"Investigating the Effect of Brain Electrical Stimulation and Cognitive-Metacognitive Rehabilitation on Depression and Cognitive Function in Elderly with Mild Cognitive Impairment"

The Effectiveness of Anodal Stimulation of Left Dorsolateral Prefrontal Cortex and Cognitive-Metacognitive Rehabilitation on Working Memory, Depression, Cognitive Flexibility and Information speed processing in Elderly with Mild Cognitive Impairment: single-case design with multiple baseline

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250126064528N1

Enrollment

Registered

2025-05-05

Start date

2025-05-10

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment. Mild cognitive disorder

Interventions

Intervention 1: Intervention group 1: Anodal Stimulation of Left Dorsolateral Prefrontal Cortex:The tDCS device is an “ActivaDose Iontophoresis” manufactured by Activa Tek, with a9-V battery serving a

Eligibility

Sex/Gender

All

Age

55 Years to 70 Years

Inclusion criteria

Inclusion criteria: Diagnosis of Mild Cognitive Impairment Comorbid with Depression by a Psychiatrist Consent to Participate in the Research and Signing of a Written Informed Consent Form No History of Mental Illness No History of Severe Cognitive Impairment, Brain Injury, Neurological Disorder, or Serious Medical Conditions No History of Personality Disorders, Schizophrenia, or Bipolar Disorder No History of Substance Abuse No Systematic Medication Use by the Patient Up to 3 Months Prior to Entry into the Study

Exclusion criteria

Exclusion criteria: -

Design outcomes

Primary

Measure	Time frame
Depression. Timepoint: At the beginning of the intervention, every 4 sessions during the intervention, at the end of the intervention, and one month after the intervention. Method of measurement: Beck Depression Inventory (BDI).;Working memory. Timepoint: At the beginning of the intervention, every 4 sessions during the intervention, at the end of the intervention, and one month after the intervention. Method of measurement: Wechsler Digit Span Subscale.;Cognitive flexibility. Timepoint: At the beginning of the intervention, every 4 sessions during the intervention, at the end of the intervention, and one month after the intervention. Method of measurement: Stroop Test.;Information processing speed. Timepoint: At the beginning of the intervention, every 4 sessions during the intervention, at the end of the intervention, and one month after the intervention. Method of measurement: Stroop Test.	—

Measure

Time frame

Depression. Timepoint: At the beginning of the intervention, every 4 sessions during the intervention, at the end of the intervention, and one month after the intervention. Method of measurement: Beck Depression Inventory (BDI).;Working memory. Timepoint: At the beginning of the intervention, every 4 sessions during the intervention, at the end of the intervention, and one month after the intervention. Method of measurement: Wechsler Digit Span Subscale.;Cognitive flexibility. Timepoint: At the beginning of the intervention, every 4 sessions during the intervention, at the end of the intervention, and one month after the intervention. Method of measurement: Stroop Test.;Information processing speed. Timepoint: At the beginning of the intervention, every 4 sessions during the intervention, at the end of the intervention, and one month after the intervention. Method of measurement: Stroop Test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Jalali

Golestan University

jalali.psycho@yahoo.com+98 17 3255 6187

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026