Underactive bladder. Other neuromuscular dysfunction of bladder
Conditions
Interventions
Intervention Group: Participants in the intervention group will receive autologous exosomes derived from their own peripheral blood. These exosomes will be isolated under laboratory conditions at cent
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age over 18 years History of idiopathic or neurogenic underactive bladder (UAB) for at least 6 months with symptoms that do not respond to previous medication and/or other treatments. Urinary incontinence (complaints of bladder problems) Post-void residual (PVR) greater than 150 mL, or complete reliance (100%) on clean intermittent catheterization (CIC) for bladder emptying.
Exclusion criteria
Exclusion criteria: Women who are pregnant or planning to become pregnant Treatment with anticoagulant medications Treatment with oral medications or other therapies for UAB in the past 6 months History of bladder radiation therapy or pelvic organ prolapse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary frequency. Timepoint: Pre-intervention and three months after intervention. Method of measurement: Bladder diary. | — |
Secondary
| Measure | Time frame |
|---|---|
| Nocturia. Timepoint: Pre-intervention and three months follow-up. Method of measurement: Bladder diary.;Bladder questionnaire score. Timepoint: Pre-intervention and three months follow-up. Method of measurement: LUTS questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSakineh Hajebrahimi
Tabriz University of Medical Sciences
Outcome results
None listed