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The effect of exercise training on hemodialysis outcomes and complications

The effect of resistance training on blood parameters, dialysis adequacy, resting heart rate and blood pressure, physical strength, fatigue and quality of life in middle-aged hemodialysis patients.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250125064514N1
Enrollment
80
Registered
2025-04-19
Start date
2025-05-22
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease (CKD). Chronic kidney disease, stage 5

Interventions

Intervention 1: Patients in the experimental group will participate in a 50-minute structured resistance training program that will be performed under the supervision of the researcher for the 1 initi

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Gender: male and female Age: middle-aged (40 to 65 years) Condition of dialysis: chronic hemodialysis -3 times a week - morning shift - Fresenius and Beibran machines (clinical file) Disease conditions: similar in terms of severity and degree, underlying diseases and medications (opinion of the attending physician and clinical file) BMI: 18 to 30, i.e. normal and overweight (measured by the researcher) Trainability and ability to perform resistance exercises (opinion and permission of the attending physician - initial assessment in the Pre-test) No special dietary or dietary restrictions (other than common restrictions in ESRD patients undergoing HD) (opinion of the attending physician and clinical file) Not doing specific exercise other than routine activities of life (interview with patient)

Exclusion criteria

Exclusion criteria: HB at study entry:less than 10 g/dl (clinical file) Resting systolic blood pressure greater than 140 mmHg within the past month (clinical file) Changes in dietary patterns and physical activity during the study compared to the beginning of the study (interview with patients)

Design outcomes

Primary

MeasureTime frame
1-Blood biochemical parameters (urea, creatinine, phosphate, potassium, sodium, albumin, CRP, lactate and hemoglobin). Timepoint: Beginning, middle (week 4) and end of the study (week 8). Method of measurement: laboratory results.;Dialysis adequacy. Timepoint: Beginning, middle (week 4) and end of the study (week 8). Method of measurement: the standard Kt/V index.;Resting heart rate (RHR). Timepoint: Beginning, middle (week 4) and end of the study (week 8). Method of measurement: Pulse Oximeter.;Resting systolic and diastolic blood pressure (BP). Timepoint: Beginning, middle (week 4) and end of the study (week 8). Method of measurement: Standard and calibrated Mercury barometer.;Physical strength (hand grip strength and trunck strength). Timepoint: Beginning, middle (week 4) and end of the study (week 8). Method of measurement: Dynamometer.;Post Dialysis Fatigue level. Timepoint: Beginning, middle (week 4) and end of the study (week 8). Method of measurement: the standard FACIT questionnaire.;Quality of life (QOF). Timepoint: Beginning, middle (week 4) and end of the study (week 8). Method of measurement: the 36-item Short Form Health Questionnaire (SF-36) containing physical dimension scales (PCS) and mental dimension scales (MCS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShiva Mashinchi

Rasht University of Medical Sciences

S_mashinchi@yahoo.com+98 13 3333 1638

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026