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fluoride concentration in saliva and biofilm following toothbrushing

Evaluation of fluoride concentration in saliva and biofilm following toothbrushing with and without rinsing in children

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250125064512N1
Enrollment
44
Registered
2025-01-29
Start date
2025-01-04
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Salivary fluoride concentration and biofilm after brushing with fluoride toothpaste in 6-7 year old children. Condition 2: Salivary fluoride concentration and biofilm after brushing with fluoride toothpaste in 9-11 year old children.

Interventions

Intervention 1: Intervention group:. Intervention 2: Intervention group two: Toothpaste containing high-concentration fluoride ions in children 9-11 years old with mouth rinsing. Intervention 3: Third

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 11 Years

Inclusion criteria

Inclusion criteria: Children 6 to 7 years old and 9 to 11 years old Children without a history of kidney disease and sensitivity to fluoride Written consent from parents or guardians Resting salivation rate is 0.1 millimeter/minute or more

Exclusion criteria

Exclusion criteria: Toothlessness Sensitivity to any of the materials used in the study Inability to retain toothpaste after brushing If they had orthodontic braces

Design outcomes

Primary

MeasureTime frame
Fluoride ion levels in plaque and saliva samples in children aged 6-7 years in Kerman city at the beginning and after tooth brushing. Timepoint: At times 1, 30, 60 minutes. Method of measurement: Chromatography device.;Fluoride ion levels in plaque and saliva samples in children aged 9-11 years in Kerman city at the beginning and after tooth brushing. Timepoint: At times 1, 30, 60 minutes. Method of measurement: Chromatography device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParnian Poureslami

Kerman University of Medical Sciences

kodrc@yahoo.com+98 34 3212 6025

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026