The effect of propofol in reducing headache after spinal anesthesia in patients undergoing lithotripsy.

Investigating the effect of propofol compared to placebo on the amount of headache after spinal anesthesia in patients undergoing lithotripsy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250122064490N1

Enrollment

Registered

2025-02-21

Start date

2025-03-10

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Headache after spinal anesthesia. Other reaction to spinal and lumbar puncture

Interventions

Intervention 1: Control group: Standard care after spinal anesthesia including bed rest, hydration, and midazolam 2 mg, fentanyl 100 micrograms, and placebo, identical to the drug propofol, at a dose

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 65 years old Class I or II anesthesia status Patient satisfaction

Exclusion criteria

Exclusion criteria: Contraindications to propofol or egg products History of allergy to propofol Having blood clotting disorders Previous spinal surgery or contraindications to spinal anesthesia History of headache and migraine disorders History of any neurological or psychiatric disorder

Design outcomes

Primary

Measure	Time frame
Headache severity. Timepoint: Beginning of surgery, recovery 6, 12, 24, 48 hours after surgery. Method of measurement: Numerical Pain Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Asadpour

Kerman University of Medical Sciences

Naeimehnaeimi53@gmail.com+98 34 3222 8034

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026