The Effect of Acetylcysteine ??on Dialysis Blood Pressure Drop

Investigating the effect of acetylcysteine ??on blood pressure drop during dialysis in hemodialysis patients: a randomized clinical study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250122064488N1

Enrollment

Registered

2025-02-01

Start date

2025-02-19

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dialysis. ????? 5 ??????? ???? ?????- ???? ?? ??????

Interventions

Intervention 1: Intervention group: Conducting the intervention for 2 months and twice a day with an oral dose of 600 mg. Intervention 2: Control group: Receive standard treatment without placebo.

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: informed consent Being on dialysis for at least 3 months

Exclusion criteria

Exclusion criteria: Active infectious disease Being Anuric

Design outcomes

Primary

Measure	Time frame
Patient's Blood Pressure Including Systolic and Diastolic Blood Pressure, Mean Arterial Pressure. Timepoint: Before, During and After Dialysis. Method of measurement: In This Study, it Will be Measured by One Person Using a Type of Sphygmomanometer.	—

Secondary

Measure	Time frame
Muscle spasm. Timepoint: Before, During and After Dialysis. Method of measurement: The patient's statements are low, medium and high.;DYSPNEA. Timepoint: Before, During and After Dialysis. Method of measurement: The patient's statements are low, medium and high.;Nausea. Timepoint: Before, During and After Dialysis. Method of measurement: The patient's statements are low, medium and high.;Chest Pain. Timepoint: Before, During and After Dialysis. Method of measurement: The patient's statements are low, medium and high.	—

Measure

Time frame

Muscle spasm. Timepoint: Before, During and After Dialysis. Method of measurement: The patient's statements are low, medium and high.;DYSPNEA. Timepoint: Before, During and After Dialysis. Method of measurement: The patient's statements are low, medium and high.;Nausea. Timepoint: Before, During and After Dialysis. Method of measurement: The patient's statements are low, medium and high.;Chest Pain. Timepoint: Before, During and After Dialysis. Method of measurement: The patient's statements are low, medium and high.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDanial Gholami

Yasouj University of Medical Sciences

danial_gholami92@yahoo.com+98 74 3333 7001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026