The effects of melatonin on Cerebral edema in patients with traumatic brain injury in besat hospital, hamedan

The effects of melatonin on Cerebral edema in patients with traumatic brain injury

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250122064482N1

Enrollment

120

Registered

2025-02-06

Start date

2025-02-19

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral edema in traumatic brain injury.

Interventions

Intervention 1: Intervention group receive melatonin tablet 5 or 10 mg daily in addition to usual treatments for cerebral edema. Intervention 2: Control group: usual treatments of cerebral edema.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Cerebral edemal Traumatic brain injury Age >18

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Brain parenchymal density. Timepoint: First day after trauma- 3rd to 5th days after trauma- 7th to 10th days after trauma. Method of measurement: Brain parenchymal density on CT scan.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMashhood aghajanloo

Hamedan University of Medical Sciences

Mashhoodaghajanloo@gmail.com0988132640041

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026