Results of combined treatment of FU-5 solution and microneedling in vitiligo

Investigating the results of the combined treatment of topical FU-5 solution and microneedling in the treatment of stable and resistant vitiligo

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250121064469N1

Enrollment

Registered

2025-02-10

Start date

2024-09-22

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitiligo. Vitiligo

Interventions

Intervention group: Combined treatment of topical 5-FU and microneedling is performed for patients. First, we perform processing on the depigmented lesions using a microneedling device, then Ebewe's 5

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Stable and resistant vitiligo patients Failure to respond to nonsurgical treatment within 6 months

Exclusion criteria

Exclusion criteria: Patients with visceral system diseases such as heart, kidney, liver Presence of other skin diseases such as psoriasis, eczema, infection Patients with cicatricial diathesis Patients with allergies to lidocaine Pregnant and breastfeeding women Possible allergy to the drug under study

Design outcomes

Primary

Measure	Time frame
Improvement of pigmentation at the treatment site. Timepoint: The patient is visited every two weeks. the treatment results are evaluated at the end of the sixth month. Method of measurement: Photographs are taken of the patients before and after treatment.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHadis.heidarzadi

Kermanshah University of Medical Sciences

babakhanymaryam@gmail.com+98 83 3827 6879

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026