with knee osteoarthritis. Primary osteoarthritis of other joints
Conditions
Interventions
Intervention 1: Intervention group: Therapeutic intervention will be performed in the form of radiation to the knee affected by osteoarthritis with a dose of 0.5 Gray per fraction and for 3 fractions,
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: Age over 55 years Pain score greater than or equal to 5/10 according to the NRS criteria With no response to medication and physiotherapy treatment (for at least three months of previous treatment) Having good general condition for radiotherapy, With osteoarthritis at stage 3 or lower
Exclusion criteria
Exclusion criteria: Receiving intra-articular corticostroid within less than 4 weeks of starting radiotherapy Patient with stage 4 osteoarthritis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee Joint pain reduction. Timepoint: Baseline assessment (before starting the clinical intervention) and the final therapy session (patient follow-up at months 1, 3, 6, 12, and 24 after the end of treatment). Method of measurement: Assessments of pain extent, pain intensity based on Visual Analogue Scale/Numeric Rating Scale criteria.;Improvement the range of motion in the knee joint motion. Timepoint: Baseline assessment (before starting the clinical intervention) and the final therapy session (patient follow-up at months 1, 3, 6, 12, and 24 after the end of treatment). Method of measurement: Investigation of joint movement restrictions according to the Western Ontario and McMaster Universities Arthritis Index (WOMAC index).;Quality of life improvement. Timepoint: Baseline assessment (before starting the clinical intervention) and the final therapy session (patient follow-up at months 1, 3, 6, 12, and 24 after the end of treatment). Method of measurement: Quality of life assessment based on the SF-36 criteria. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reducing pain score based on Visual Analogue Scale/Numeric Rating Scale citeria, Improvement of joint movement restrictions according to the Western Ontario and McMaster Universities Arthritis Index (WOMAC index), as well as improvement of life quality based on the SF-36 criteria. Timepoint: Baseline assessment (before starting the clinical intervention) and the final therapy session (patient follow-up at months 1, 3, 6, 12, and 24 after the end of treatment). Method of measurement: The study parameters were evaluated using a set of subjective criteria reported by the patient (including assessments of pain extent, pain intensity based on Visual Analogue Scale/Numeric Rating Scale citeria, level of individual functional limitations, and joint movement restrictions according to the Western Ontario and McMaster Universities Arthritis Index (WOMAC index), as well as quality of life based on the SF-36 criteria) and objective criteria (including clinical examination of the knee joint and evaluation with a triple-phase bone scan/SPECT CT). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTahereh Bastami
Tehran University of Medical Sciences
Outcome results
None listed