Stroke. Stroke, not specified as haemorrhage or infarction
Conditions
Interventions
Intervention 1: Intervention group: The intervention group will consume two synbiotic capsules with the brand name Lactocare (500 mg) daily, one after lunch and the other after dinner. Intervention 2:
Sponsors
Semnan University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: Male gender Willingness to participate in the study and have written consent Age 40 - 85 years old Focal neurological deficit lasting at least 60 minutes MRI consistent with clinical diagnosis of acute ischemia NIHSS stroke scale less than 15 with at least 2 points from sections 5 and 6 (motor)
Exclusion criteria
Exclusion criteria: Patients with severe heart, liver, kidney and other organ failure, or malignancy, metabolic diseases Having certain conditions such as immunodeficiency and AIDS, taking immunosuppressive drugs or chemotherapy. Having symptoms of infection (such as high fever, chills and persistent cough) Patients with a history of allergies to drugs, foods, or probiotics MRI evidence of brain tumor or abscess, brainstem or cerebellar infarction, significant cerebral edema, subarachnoid hemorrhage, or primary intracerebral hemorrhage Severe concomitant systemic disease that limits life expectancy History of ventricular dysrhythmia, acute myocardial infarction, or acute cardiovascular conditions that interfere with interpretation Neurological signs and symptoms that improve during the study Pre-existing medical conditions that may interfere with the study Patient unwillingness to continue treatment Patient discharged and transferred to another department or center Death before the end of the treatment period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain injury. Timepoint: Evaluation of brain injury is performed before the intervention and at the end of one week. Method of measurement: MRI. | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory factors and oxidative stress. Timepoint: Measurement of inflammatory factors and oxidative stress is performed before the intervention and at the end of one week. Method of measurement: ELISA technique. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahein Momenabadi
Semnan University of Medical Sciences
Outcome results
None listed