Duchenne patients. Muscular dystrophy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Duchenne patients with a proven in-frame genetic mutation are selected. Movement disorder in lower limbs with age between 8 and 20 years are selected.
Exclusion criteria
Exclusion criteria: Patients with severe movement disorder of the lower limbs and pelvic girdle muscles leading to the inability to walk are not included in the study. People with skin lesions in the areas being treated are excluded. Have no history of allergy to biological products.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle thickness. Timepoint: At the beginning of the study (before the start of the intervention), 1 and 3 months after the start of the treatment. Method of measurement: Ultrasound imaging and sequential image processing.;Young modulus. Timepoint: At the beginning of the study (before the start of the intervention), 1 and 3 months after the start of the treatment. Method of measurement: Ultrasound imaging and sequential image processing.;Shear modulus. Timepoint: At the beginning of the study (before the start of the intervention), 1 and 3 months after the start of the treatment. Method of measurement: Ultrasound imaging and sequential image processing. | — |
Secondary
| Measure | Time frame |
|---|---|
| Muscle activity. Timepoint: At the beginning of the study, 1 and 3 months after treatment. Method of measurement: Elastic modulus of muscles. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tarbiat Modares university