Skip to content

The effect of probiotics on brucellosis

The effect of probiotics on clinical symptoms and paraclinical findings of patients with brucellosis: A randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250110064341N1
Enrollment
24
Registered
2025-01-26
Start date
2025-04-03
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brucellosis. Brucellosis

Interventions

Intervention 1: Intervention group: Receiver of Probiotic + Standard treatment of Brucellosis. Intervention 2: Control group: Receiver of Placebo + Standard treatment of Brucellosis.

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Having active brucellosis in the body Age between 18 to 60 years

Exclusion criteria

Exclusion criteria: having concurrent infections such as tuberculosis Not consuming probiotics

Design outcomes

Primary

MeasureTime frame
Clinical Symptoms of Brucellosis include fever, sweating, fatigue, weight loss, joint pain, muscle pain, etc. Timepoint: baseline - 4weeks - 8weeks after starting intervention. Method of measurement: Questions to ask the patient about the clinical symptoms of brucellosis.;Laboratory criteria of Brucellosis. Timepoint: baseline - 4weeks - 8weeks after starting intervention. Method of measurement: Blood sampling and testing for Wright, Coombs Wright, 2ME, IgG, and IgM.

Secondary

MeasureTime frame
CRP (C-Reactive protein) and LFT. Timepoint: Baseline - 4 weeks - 8 weeks after intervention. Method of measurement: Blood sampling and testing for CRP, AST, ALT, AlkP.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Alireza Khatami Bidgoli

Kashan University of Medical Sciences

kermanimasi1@gmail.com+98 31 5547 2939

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026