Condition 1: male infertillity. Condition 2: Male erectile dysfunction. Condition 3: Premature ejaculation. Condition 4: Male orgasmic disorder. Condition 5: Hypoactive sexual desire disorder. Condition 6: Intercourse satisfaction. Condition 7: Overall sexual satisfaction. Male infertility Male erectile dysfunction Premature ejaculation Male orgasmic disorder Hypoactive sexual desire disorder
Conditions
Interventions
Intervention 1: Intervention group: 42 patient receive 1000 mg of alcoholic extract of Urtica pilulifera seeds and 200 mg of Avicel daily (in 3 capsules, morning and night) for 90 days. Intervention 2
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Abnormality of at least one sperm parameter (concentration less than 16 million per milliliter, percentage of progressive motile sperm less than 30%, or normal sperm shape less than 4%) in a spermogram test performed in the past 6 months
Exclusion criteria
Exclusion criteria: No sperm in spermogram test Obstructive diseases of the genital tract Vasectomy History of previous surgeries on the testicle Cryptorchidism Epididymitis and orchitis Sexual transmitted diseases Cancer Previous History chemotherapy and radiation therapy Substance addiction Known sensitivity to any herbal product Possibility of developing infertility due to delay in treatment Age above 45 years of the patient's spouse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total sperm number (per ejaculate). Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: Semen analysis.;Sperm concentration (sperm number per ml). Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: Semen analysis.;Total motility of sperm (percentage). Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: Semen analysis.;Progressive motility of sperm (percentage). Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: Semen analysis.;Normal sperm shape (percentage). Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: Semen analysis.;Semen volume (ml). Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: Semen analysis.;Semen pH. Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: Semen analysis.;Liquefaction time. Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: Semen analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| IIEF questionnaire results. Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: IIEF questionnaire.;HISD questionnaire results. Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: HISD questionnaire.;SQOL-M questionnaire results. Timepoint: Before the intervention, upon completion of the intervention (after 90 days). Method of measurement: SQOL-M questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactJavad Saghafi
Tehran University of Medical Sciences
Outcome results
None listed