Female infertility. Female infertility
Conditions
Interventions
Intervention 1: Intervention group: In patients in the duostim group, 4 mg of estradiol was started on day 21 of the previous cycle and continued until the second day of menstruation. On days 2-3 of t
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
24 Years to 44 Years
Inclusion criteria
Inclusion criteria: Anti-Mullerian hormone (AMH) equal to or less than 1.2 ng/ml or an antral follicle count (AFC) equal to or less than 5 on day 3 of the menstrual cycle or fewer than five eggs retrieved in the previous cycle or serum FSH concentration between 10 and 19 IU/L or no evidence of primary ovarian insufficiency, which includes FSH less than 20 IU/L
Exclusion criteria
Exclusion criteria: Endometriosis higher than grade 3 Contraindications for the use of gonadotropins Couples with severe male factor infertility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of recovered metaphase II oocytes. Timepoint: 36 hours after the intervention. Method of measurement: The retrieved oocytes in both groups and each stage are incubated for 2-4 hours, after which the cumulus and corona radiata cells will be removed from the eggs. The oocytes are then evaluated. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of oocytes retrieved. Timepoint: 36 hours after the intervention. Method of measurement: The retrieved oocytes in both groups and each stage are incubated for 2-4 hours, after which the cumulus and corona radiata cells will be removed from the eggs. The oocytes are then evaluated. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahla Farzipour
Ardabil University of Medical Sciences
Outcome results
None listed