Late onset neonatal sepsis. Bacterial sepsis of newborn
Conditions
Interventions
Intervention 1: Control group: The antibiotics include meropenem 30mg/kg q8hr and vancomycin 10mg/kg q8hr, which were prescribed for 7 days through the intravenous route and manufactured by the Dana c
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
3 Days to 90 Days
Inclusion criteria
Inclusion criteria: all neonates age more than 3 days old suspicious for sepsis neonates having a birth weight which is more than 2 kilograms diagnosed with a late onset neonatal sepsis neonates more than 3 days old with fever and central core temperature more than 38 degrees or less than 36 degrees centigrade neonates with a positive blood or urine culture neonates aged more than 3 days old with tachycardia or tachypnoea neonates aged more than 3 days old with leukocytosis or leukopenia
Exclusion criteria
Exclusion criteria: birth weight less than 2 kilogram Premature neonates with gestational age of less than 37 weeks congenital anomalies ventilator dependent neonates asphyxiated neonates neonates who can not be feed orally
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sepsis scores which are probable and highly probable. Timepoint: sepsis scores were calculated before treatment and 72 hours after treatment. Method of measurement: blood tests include blood culture, complete blood count (CBC), C-reactive protein (CRP), urine culture, clinical status. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSara Nikafarin
Iran University of Medical Sciences
Outcome results
None listed