Comparing the effects of chamomilla mouthwash and nystatin in the treatment of denture stomatitis

Comparison of Therapeutic Effect of Mouthwash Containing Matricaria chamomilla Extract and Nystatin Suspension on Patients with Denture Stomatitis- a randomized clinical trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241231064232N1

Enrollment

Registered

2025-02-24

Start date

2025-01-20

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

denture stomatitis.

Interventions

Intervention 1: Intervention group: Using mouthwash containing chamomile/ Patients are asked to swish 10 cc of chamomile mouthwash in their mouth 3 times (every 8 hours) and gargle for 1 minute, then

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy individuals with maxillary complete dentures and denture stomatitis (type II)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Fungi load. Timepoint: day 0, 7, and 14. Method of measurement: Colony cultivation and counting.;Lesion diameter. Timepoint: day 0, 7, and 14. Method of measurement: measuring with probe.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Ebrahimi Saravi

Mazandaran University of Medical Sciences

poyarabiee@gmail.com+98 11 3324 4014

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026