The effect of vaginal RF on the expression of TGF-ß and the activity of lysyl oxidase in the collagen synthesis pathway in the vaginal samples of patients with pelvic disorders

Vaginal Radiofrequency in Women with pelvic disorders on collagen synthesis pathway

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241231064230N1

Enrollment

Registered

2025-02-22

Start date

2025-03-05

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pelvic disorders including urinary incontinence, vaginal dryness, sexual dysfunction.

Interventions

Intervention 1: Intervention group: Vaginal RF performed in women with symptoms of urinary incontinence or vaginal dryness or sexual dysfunction. Intervention 2: Control group: Women with symptoms of

Eligibility

Sex/Gender

Female

Age

35 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients With Urine Incontinency Patients With Dried Vagina Patients With Sexual Disorders

Exclusion criteria

Exclusion criteria: Patients With Infection Patients With Systemic or Psychological Disease Patients With Vascular And Cardiac Disease Patients With Connective Tissue or Genetic Disorders

Design outcomes

Primary

Measure	Time frame
Vaginal Radio Frequency. Timepoint: Before starting RF and 6 weeks and six months after RF. Method of measurement: Real time PCR.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTayebeh Rasteagr

Tehran University of Medical Sciences

trastegar2002@gmail.com+98 21 6405 3404

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026