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Effectiveness of Proprioceptive Neuromuscular Exercises in patients that have undergone Total Knee Replacement Surgery

Effectiveness of Proprioceptive Neuromuscular Exercises in improving Knee Range of Motion, Functional Ability, and Balance in Total Knee Arthroplasty Patients; A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241230064219N1
Enrollment
32
Registered
2025-05-11
Start date
2025-05-15
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The condition under study is knee osteoarthritis. Systematic analysis for a Global burden of disease study done in 2021, shows that OA was the 7th ranked cause of Years lost due to disability (YLD’s) in adults aged over 70 years and knee was the most common site of Osteoarthritis. While the post-operative recovery process differs from person to person, most of the patients report a marked improvement in the outcomes such as pain however, it has been found that muscle atrophy, neuromuscular impai

Interventions

Intervention 1: Control group: Participants in the control group will receive exercises such as (1) knee flexion with assistance from a belt in supine lying, (2) quadriceps on fulcrum in supine lying,

Sponsors

Khyber Medical University Peshawar
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Individuals with unilateral Total Knee Arthroplasty Procedure Participants who underwent 1 weeks after Total Knee Arthroplasty surgery Patients who can walk for 10 meters on ground at a comfortable speed (with or without assistive device) Patients having Mini Mental State Examination score of 24 or more

Exclusion criteria

Exclusion criteria: Individuals who had undergone total knee replacement previously. Individuals who had a re-operation for total knee arthroplasty (revision arthroplasty or manipulation under anesthesia). Past surgical history of any orthopedic procedure at lower limbs. History of fractures at lower limbs. Individuals with multiple medical comorbidities such as metabolic disorders, cancers. Individuals with cardiovascular conditions such as Ischemic heart disease or Peripheral Vascular Disease. Individuals with Cognitive and neurological disorders i.e. stroke, neuropathy. Individual with neuromuscular disorders i.e., Multiple Sclerosis. Individuals on Beta Blockers and uncontrolled Hypertension. Individuals with multiple musculoskeletal conditions other than knee Osteoarthritis

Design outcomes

Primary

MeasureTime frame
Range of Motion: The knee flexion and extension Range of Motion. Timepoint: before intervention and 2 weeks after intervention. Method of measurement: Range of Motion will assessed using a goniometer with patient in supine position and in saggital plan of movement.

Secondary

MeasureTime frame
Secondary outcome variable is Functional Activity. Being bed ridden in the initial phases after total knee replacement detrimentally effects the level of functional activity as many patients avoid to move at all. Timepoint: before intervention and 2 weeks after intervention. Method of measurement: The Timed Up and Go (TUG) test will be used to assess functional activity. It is a highly reliable tool with inter- and intra-rater reliability scores of r=0.98 to 0.99. At the starting point, participants will be seated in an chair. When the signal to begin is given, they must get up from the chair, move three meters to a point, quickly turn towards the TKR side, and then get back in the chair. The time to complete the task will be recorded.;Balance. Timepoint: before intervention and 2 weeks after intervention. Method of measurement: Short form of Berg Balance scale will be used to assess the balance performance of the participants.

Countries

Pakistan

Contacts

Public ContactMunazza Shah

Institute of Physical Medicine and Rehabilitation, Khyber Medical University

shah.munazza997@gmail.com+92 91 5812299

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026