Acute Ischemic Stroke. Cerebral infarction, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Routine treatment includes antiplatelet and atorvastatin plus melatonin tablets 20 mg daily for 5 days. Intervention 2: Control group: Routine treatment with placeb
Sponsors
Oroumia University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age 18 to 80 years Ability and willingness to participate in the study (obtaining informed consent) Acute stroke that occurred within 7 days prior to admission to the ward Diagnosis of acute ischemic stroke confirmed by computed tomography (CT) or magnetic resonance imaging (MRI) at the time of admission
Exclusion criteria
Exclusion criteria: Patient with a history of heart attack Primary hemorrhagic stroke Pre-stroke diagnosis indicating significant decline in mental function or impairment A valid neurological disease in addition to stroke, such as Parkinson's disease Severe liver, kidney, or thyroid disease, or heart failure, respiratory failure, or other organ failure Chronic inflammatory diseases, immune or hematological disorders History of depression (clinical diagnosis or previous treatment) or other mental disorders Patients who are not accessible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • Size of cerebral infarction (volume of ischemic area). Timepoint: 1. Baseline (before intervention) – in the first 7 days after stroke and before treatment begins, 2. Follow-up (follow-up) – three months after intervention. Method of measurement: Brain CT scan. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Rizvan Norouzzadeh
Oroumia University of Medical Sciences
Outcome results
None listed