Effect of magnesium sulfate in changes in neonatal indices

Comparison of the effects of 12-hour and 24-hour magnesium sulfate on changes in neonatal indices in infants born after PPROM (Premature Preterm Rupture Of Membrane) before 32 weeks of gestation

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241229064202N1

Enrollment

Registered

2025-01-21

Start date

2024-12-21

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature rupture of membranes. Preterm premature rupture of membranes, onset of labor within 24 hours of rupture

Interventions

Intervention 1: First, 6 g of MgSO4 dissolved in 100 ml of normal saline will be infused for 20 minutes to reach the dose load.Mothers in group A will receive 2 g of this solution every hour by infusi

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Hospitalized in high risk section Premature rupture of membranes Weeks 28 to 32 of pregnancy

Exclusion criteria

Exclusion criteria: Twin pregnancy Previous administration of magnesium sulfate Suspected chorioamnionitis

Design outcomes

Primary

Measure	Time frame
Changes in neonatal indices. Timepoint: During 24 hour after Surgery. Method of measurement: Clinical examination and complete the checklist.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShervin Tabrizian

Ardabil University of Medical Sciences

Shervintabrizian@gmail.com+98 45 3324 8888

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026