Chronic obstructive pulmonary disease (COPD). Chronic obstructive pulmonary disease with (acute) exacerbation
Conditions
Interventions
Intervention 1: Control group: placebo, A placebo capsule with the same appearance as the drug. Intervention 2: Intervention group: Treated with one Lactoker synbiotic capsule (Biot Khamtir Company, I
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: COPD patients with GOLD stage two to four, age over 50 years, and with a history of at least one COPD exacerbation leading to hospitalization during the last year
Exclusion criteria
Exclusion criteria: Patients with a history of previous pulmonary disease (other than COPD), acute coronary syndrome, CHF and hospitalization due to acute exacerbation of COPD in the last three weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in spirometric indices. Timepoint: Before, 6 months after the intervention. Method of measurement: Perform spirometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dyspenea. Timepoint: Before and 6 months after the intervention. Method of measurement: MMRT,CAT index.;Quality of Life. Timepoint: Before and 6 months after the intervention. Method of measurement: questionnaire.;Severity of the disease. Timepoint: Before and 6 months after the intervention. Method of measurement: BODY index.;Number of exacerbations (outpatient and hospitalization). Timepoint: Before and 6 months after the intervention. Method of measurement: Question from the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Hossein Aref
Yazd University of Medical Sciences
Outcome results
None listed