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The effect of ointment containing Green Tea extract and Peganum harmala in the treatment of Genital Warts in Women

Investigating the effect of ointment containing Green Tea extract and Peganum harmala in the treatment of Genital Warts in Women: a controlled randomized clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241225064163N2
Enrollment
60
Registered
2025-05-17
Start date
2025-05-20
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Genital warts. Anogenital (venereal) warts

Interventions

Intervention 1: Intervention group 1: gel containing green tea extract and pecan seeds in a 50-50 ratio. Intervention 2: Control group: gel containing green tea extract. Intervention 3: Intervention g

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: The individual must not have any specific medical illnesses. They should have no other sexually transmitted diseases (STDs) In the past 6 months, they should not have been under psychiatric supervision and should not be taking psychiatric medications. They must not be allergic to green tea or pennyroyal seeds They should not have speech or behavioral disorders that hinder communication with the researcher. They must not have genital warts inside the vagina Genital warts should be limited to the skin. The number of lesions should be between 2 and 30 The surface area of lesions should be between 2 and 600 square millimeters Their spouse should not have genital warts They should have no history of using specific medications. Both they and their spouse should have only one sexual partner.

Exclusion criteria

Exclusion criteria: They are breastfeeding or pregnant. They are smoker They are infected with other STDs

Design outcomes

Primary

MeasureTime frame
Number and size of external genital wart lesions. Timepoint: Every two weeks until the 10th week. Method of measurement: The patient is examined by the researcher and all areas of the genital area such as the posterior foreskin, labia majora, groin, pubic and anal areas, and perianal are examined for the presence of lesions and the number and size of the lesions are recorded. To determine the initial size of the lesion, the two main perpendicular diameters of each lesion are measured in millimeters with a ruler and the area of ??each lesion is obtained from the product of these two diameters.

Secondary

MeasureTime frame
Occurrence of new lesions. Timepoint: Every two weeks. Method of measurement: Observation.;Occurrence of reactions and side effects. Timepoint: Every two weeks. Method of measurement: Questioning the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDavoud Salarbashi

Gonabad University of Medical Sciences

davoud.salarbashi2@gmail.com+98 915 303 0852

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026