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Neuropathy and physiotherapy

Investigating the efficacy of physiotherapy on lowering the neuropathic symptoms of type-2 diabetic patients who received Gabapentin in a dose-dependent manner: a clinical trial study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241221064123N1
Enrollment
135
Registered
2025-06-06
Start date
2025-08-23
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes with peripheral neuropathy. Diabetes mellitus due to underlying condition with diabetic nephropathy

Interventions

Intervention 1: Intervention group: Type 2 diabetic patients with peripheral neuropathy in the intervention group receive 300 mg of gabapentin and complete 10 sessions of physiotherapy. The control gr

Sponsors

Zabol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Informed Consent Peripheral neuropathy and type two diabetes 30 to 70 years Patients should only use gabapentin as a treatment for neuropathy.

Exclusion criteria

Exclusion criteria: Having skin lesions or swelling that disrupts nerve conduction. Infected with neuropathies related to malnutrition and alcoholic neuropathy. To undergo the amputation. Combining Gabapentin with Other Pain Medications

Design outcomes

Primary

MeasureTime frame
Changes in symptoms of peripheral neuropathy. Timepoint: Before and after intervention (0-21 days). Method of measurement: Pain level, examination of the neuromuscular strip.

Secondary

MeasureTime frame
Serum concentration of TNF-a, picograms/microliter. Timepoint: Before and after intervention. Method of measurement: ELISA.;C-Reactive Protein. Timepoint: Before and after intervention. Method of measurement: Nephelometry method.;Visual analogical pain scores. Timepoint: Numerical. Method of measurement: Of 0 (least) to 10 (most) pain.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Poursamimi

Zabol University of Medical Sciences

javadpoursamimi@gmail.com+98 54 3223 0768

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026