Vulvovaginal candidiasis. Candidiasis of vulva and vagina
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Being married Being monogamous The presence of clinical symptoms indicative of vulvovaginal candidiasis Positive result of the direct microscopy test of vaginal discharge Positive result of the vaginal discharge culture test No history of any known medical condition No allergy to Origanum vulgare plant and clotrimazole Completion of a written informed consent form
Exclusion criteria
Exclusion criteria: Pregnancy Breastfeeding Menopause Abnormal vaginal bleeding Body mass index (BMI) = 30 History of recurrent vulvovaginal candidiasis infections (4 or more episodes per year) History of known chronic diseases such as diabetes, hypertension, heart disease, immune system disorders and epilepsy Use of broad-spectrum antibiotics within the past two weeks Use of immunosuppressive drugs, corticosteroids or contraceptive pills Use of oral or vaginal medications related to genital infections within the past two weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vaginal discharge. Timepoint: Before the intervention and one week after completing the treatment course. Method of measurement: Taking the patient's history and clinical examination.;Vaginal pH. Timepoint: Before the intervention and one week after completing the treatment course. Method of measurement: pH indicator strips.;Gram staining of vaginal discharge smear test. Timepoint: Before the intervention and one week after completing the treatment course. Method of measurement: Gram staining of vaginal discharge smear.;Vaginal discharge culture. Timepoint: Before the intervention and one week after completing the treatment course. Method of measurement: Vaginal discharge culture on CHROMagar candida medium.;Complete recovery from vulvovaginal candidiasis. Timepoint: One week after completing the treatment course. Method of measurement: Taking the patient's history, clinical examination, Gram staining of vaginal discharge smear and vaginal discharge culture on CHROMagar candida medium.;Vulvovaginal itching. Timepoint: Before the intervention and one week after completing the treatment course. Method of measurement: Taking the patient's history.;Vulvovaginal erythema. Timepoint: Before the intervention and one week after completing the treatment course. Method of measurement: Clinical examination.;Vulvovaginal burning. Timepoint: Before the intervention and one week after completing the treatment course. Method of measurement: Taking the patient's history. | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary burning. Timepoint: Before the intervention and one week after completing the treatment course. Method of measurement: Taking the patient's medical history.;Dyspareunia. Timepoint: Before the intervention and one week after completing the treatment course. Method of measurement: Taking the patient's medical history.;Side effects. Timepoint: One week after completing the treatment course. Method of measurement: Taking the patient's medical history. | — |
Countries
Iran (Islamic Republic of)
Contacts
Ahvaz University of Medical Sciences