Local Anesthesia for Tooth Extraction

Effectiveness of Local Anesthetic Infiltration with Articaine 4% in Comparison to Inferior Alveolar Nerve Block with Lidocaine 2% for Mandibular 1st Molar Extraction

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241220064111N1

Enrollment

100

Registered

2025-01-11

Start date

2024-11-01

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries, Tooth Fracture, destructive and non-restorable Mandibular 1st. Molar. Dental caries

Interventions

Intervention 1: The first group will receive a buccal and lingual infiltration injection of 1.8 ml of 4% articaine + 1:100,000 epinephrine local anesthetic pre-operatively using a dental syringe. Inte

Eligibility

Sex/Gender

All

Age

18 Years to 63 Years

Inclusion criteria

Inclusion criteria: Healthy subject with no systemic disease Subject diagnosed for extraction of lower 1st. Molar

Exclusion criteria

Exclusion criteria: Patients with chronic Cardio-vascular disease Patients with infectious diseases Patients allergic to local anesthetic drug Pregnant ladies

Design outcomes

Primary

Measure	Time frame
Local anesthetic technique. Timepoint: 5 minutes. Method of measurement: patient description.	—

Countries

Iraq

Contacts

Public ContactHassan E. Al-essa, Sinan A. Shwailiya

College of Dentistry/University of Babylon

dent.sinan.a.shwailiya@uobabylon.edu.iq+964 781 565 8001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026