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The evaluation of four plants extract effectiveness on renal stone passage

The evaluation of four plants extract effectiveness on renal stone passage in patients whom underwent extracorporeal shockwave lithotripsy, A double blind randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241219064101N2
Enrollment
62
Registered
2025-03-11
Start date
2025-03-10
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A study of patients with kidney stones who are candidates for extracorporeal lithotripsy. Calculus of kidney

Interventions

Intervention 1: Intervention group: this group, which includes 31 eligible patients, will be given antibiotics, painkillers, and extracts of four plants (nettle, thistle, horsetail, celery), and patie

Sponsors

Nooshin Shahd Urmia Company
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with kidney stones and candidates for extracorporeal shockwave lithotripsy The Hounsfield unit of the stone18 years The distance between the stone and the skin surface< 10 cm The stone size is between 1-2 cm

Exclusion criteria

Exclusion criteria: Febrile patients or active UTI History of renal lithotripsy and DJ insertion Not consenting to participate in the study Any complications during or after ESWL Failure to comply their post-lithotripsy follow-up. Any anatomical abnormalities in the kidney undergoing lithotripsy History of CT Scan for any reason in the past year Pregnant women and children. Consumption of antiplatelet and anticoagulant drugs Consumption of other drugs due to any underlying disease. History of allergy to the ingredients of the four-herb extract drug

Design outcomes

Primary

MeasureTime frame
Percentage of people who completely passed kidney stones after ESWL. Timepoint: forty days after lithotripsy and drug consumption. Method of measurement: Before stone crushing, we subject all patients to a CT scan of the abdomen and pelvis without injection to obtain accurate information about the stone, and we request a urine culture test for all patients to detect a possible urinary tract infection. Then the patients are subjected to stone crushing by an experienced personnel in the field of extracorporeal stone crushing and by a single device.40 days after stone crushing, patients are subjected to kidney ultrasound by an experienced radiologist and the presence or absence of stones and the size of stone remains are checked.;Stone location. Timepoint: Before lithotripsy and forty days after lithotripsy and drug consumption. Method of measurement: Before lithotripsy, we subject all patients to a CT scan of the abdomen and pelvis without injection to obtain accurate information about the stone, and we request a urine culture test for all patients to detect a possible urinary tract infection. Then the patients are subjected to stone crushing by an experienced personnel in the field of extracorporeal stone crushing and by a single device.40 days after stone crushing, patients are subjected to kidney ultrasound by an experienced radiologist and the presence or absence of stones and the size of stone remains are checked.;Stone size. Timepoint: Before lithotripsy and forty days after lithotripsy and drug consumption. Method of measurement: We perform a non-injection CT scan of the abdomen and pelvis before lithotripsy to obtain accurate information about the stone, and we request a urine culture test for all patients to detect possible urinary tract infection. Then, patients undergo lithotripsy by an experienced staff in the field of extracorporeal lithotripsy using a single device. Patients undergo renal ultrasound 40 days after lithotripsy by an experienced radiologist

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhossein Rahavian

Yazd Shahid Sadoughi University of Medical Sciences Campus

amirrahavian@yahoo.com+98 35 3525 0480

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026