knee osteoarthritis. Primary generalized (osteo)arthritis
Conditions
Interventions
Intervention 1: Intervention group A : The treatment for group A will be mesotherapy, which involves injecting a mixture of 2 ml of 2% lidocaine and 100 units of calcitonin on days 1, 8, and 15. This
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Presence of pain and other clinical symptoms of knee osteoarthritis within the past month Age between 40 and 70 years Absence of any disease around the affected joint
Exclusion criteria
Exclusion criteria: Diabetes rheumatic and collagen vascular diseases and gout and lupus Concurrent radiculopathy Nerve injury and neuropathies Brucellosis Body mass index greater than 42 History of knee replacement in the affected side History of trauma and fracture of the affected joint Bleeding disorders Inability to communicate and complete questionnaires History of allergy and hypersensitivity reactions to the medications used History of significant liver, kidney, and cardiopulmonary disorders History of intra-articular or periarticular injections in the affected joint within the past 3 months Pregnant women Lower extremity deformities Individuals with cancer Individuals using anticoagulant medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reducing pain and improving patient function. Timepoint: Assessing the level of knee pain in patients before the injection and in the second, fourth, eighth, and twelfth weeks after the injection, as well as completing the VAS, WOMAC, and OKS questionnaires before the injection and in the second, fourth, eighth, and twelfth weeks after the injection. Method of measurement: The Western Ontario and McMaster Universities Arthritis Index and Visual Analogue Scale and Oxford Knee Score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDaniyal Emami
Shiraz University of Medical Sciences
Outcome results
None listed