Methadone vs Morphine for Pain Relief in Lumbar Spine Disc Surgery Patients

A Comparison of Intramuscular Methadone and Morphine for Pain Relief in Lumbar Spine Disc Surgery Patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241219064099N2

Enrollment

Registered

2025-11-11

Start date

2025-11-22

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Fusion Surgery Patients. Fusion of spine, lumbar region

Interventions

Intervention 1: Intervention group 1: Methadone. Intervention 2: Intervention group 2: Morphine.

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 to 70 years ASA physical status class I or II scheduled for lumbar disc surgery

Exclusion criteria

Exclusion criteria: History of opioid or substance abuse Presence of chronic diseases Radicular pain Psychiatric disorders History of seizures Mental retardation Decreased level of consciousness Hemodynamic instability

Design outcomes

Primary

Measure	Time frame
Pain score (VAS). Timepoint: 4 , 8, 12, 24. Method of measurement: VAS.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeinab Babaei Nesami

Babol University of Medical Sciences

zeinab.babaei@gmail.com+98 11 3219 9206

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026